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How Exosomes in Skincare Are Transforming Beauty Routines


Staff member
Dec 14, 2023
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Proven to have astounding results in several skincare issues, exosomes have taken the beauty industry by storm.

Exosomes regenerate skin (without invasive techniques) by sending signals at a cellular level to boost the natural repair process and achieve youthful-looking skin.

A revolutionary ingredient transforming the landscape of skincare, exosomes stimulate the production of collagen and elastin, the building blocks of skin.

Understanding Exosomes​

Increasingly used in antiaging creams, exosomes have become a pivotal ingredient in skincare used for skin regeneration properties, improved elasticity, firmness, and overall health.

Moreover, while exosomes activate skin cells while decelerating aging, they do not contain DNA, thus avoiding the risks of disease transfer or cell rejection. [1]

The Regenerative Power of Exosomes​

Exosomes enhance collagen production by up to 700% and elastin production by 300%. [2]

Exosomes have anti-inflammatory properties, which are critical in combating aging signs like unevenness, loss of elasticity, and wrinkles.

Exosomes in Skincare Products​

Highly effective in skin repair, firming, and lifting, exosome products are revolutionizing the skincare landscape.

Calecim’s skincare line exemplifies this innovative shift with stem cell-derived exosome products rich in growth factors that contribute significantly to skin rejuvenation.

Moreover, exosome skincare products enhance collagen production and elasticity, improving skin firmness and reducing pigmentation issues.

Exosomes in Skincare Products

Clinical studies on Calecim’s active ingredient, PTT-6, show remarkable results in rejuvenating older skin cells, including a substantial increase in elastin and hyaluronic acid production.

The result improved skin density, plumpness, and diminished fine lines – essential to achieving smooth makeup and youthful appearance.

Calecim’s range, comprising products like the Professional Microneedling Serum and Multi-Action Cream, has unique rejuvenating benefits.

Designed for both professional and personal use, these products leverage the power of exosomes to deliver significant anti-aging effects, making them a standout example in the realm of exosome-based skincare solutions.

Exosome Therapy in Skin Rejuvenation​

Offering a wide range of benefits, exosome stem cell skincare products have gained worldwide popularity:

  • Removes thin line wrinkles
  • Rejuvenates skins
  • Corrects uneven skin texture
  • Fights dull skin complexion
  • Improves the look of acne scars
  • Minimizes enlarged pores
  • Fights skin pigmentation

Exosome therapy is also effective in post-laser treatments, helping seal the skin and reduce potential allergic reactions.

The procedure involves applying exosomes, which feel like clear aloe vera gel, immediately after treatments like microneedling or laser, allowing deeper skin layer absorption and enhanced rejuvenation.

Exosomes pose no additional risks when combined with these treatments; in fact, they contribute to face serum benefits.


Exosome therapy is ideal for patients seeking quick recovery and enhanced results from laser treatments.

It’s an ideal option for those wanting natural improvement without resorting to fillers or Botox.

It’s also an alternative for those uncomfortable with treatments like PRP (Platelet-Rich Plasma).

The therapy is suggested to be performed by certified dermatologists or plastic surgeons, given its impact beyond the skin barrier.

The Future of Exosomes in Skincare​

The potential of exosomes in beauty treatments is vast, with experts already incorporating them in topical skincare for eye wrinkles, antiaging creams, and pharmaceutical applications.

This innovative approach represents a significant leap in skincare technology, promising more advanced and effective treatments and products in the future.

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[1] Kalluri, R. and LeBleu, V.S. (2020) ‘The biology, function, and biomedical applications of exosomes’, Science, 367(6478). doi:10.1126/science.aau6977.

[2] Trentini, M. et al. (2022) ‘Apple derived exosomes improve collagen type I production and decrease mmps during aging of the skin through downregulation of the NF-ΚB pathway as mode of action’, Cells, 11(24), p. 3950. doi:10.3390/cells11243950.
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